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Oral Bisphosphonates Once 2004 analysis proved the hyperlink between Fosamax and osteonecrosis of the jaw, lawsuits against Merck started. Lawsuits fosamax cover side effects such as bone fractures, esophagus issues, musculoskeletal ache, and osteonecrosis of the jaw. fosamax Bisphosphonates are used for treating osteoporosis and bone pain from ailments such as metastatic breast cancer, multiple myeloma, and Paget's illness.Bisphosphonates strengthen bone by inhibiting bone removal by osteoclasts.New bone is laid down by cells referred to as osteoblasts whereas old bone is removed by cells referred to as osteoclasts.Alendronate is in a class of medications called bisphosphonates.The bisphosphonate class includes etidronate , ibandronate , pamidronate , risedronate , and tiludronate . The Bisphosphonates: Fosamax, Actonel, Boniva, Reclast Over the counter fosamax alternative canada. Because food interferes with the physique’s absorption of Fosamax, the drug must be taken on an empty abdomen with no less than six ounces of plain water. FOSAMAX is a pill containing the active substance alendronic acid and belongs to a group of non-hormonal medicines called bisphosphonates. FOSAMAX prevents the lack of bone that occurs in women after they've been via the menopause and helps to rebuild bone.