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London, London, UK; 3Leids Universitair Medical Center, Leiden, The Netherlands Aims: The association of CYP3A5, CYP3A4 and ABCB1 SNPs with ciclosporin (CsA) pharmacokinetics is controversial.

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Tacrolimus (TAC) and sirolimus (SRL), two commonly used immunosuppressive agents, have demonstrated contrasting immunoregulatory effects.

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